Dihydroartemisinin enhances VEGFR1 expression through up-regulation of ETS-1 transcription factor
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منابع مشابه
Expression of E1AF, an ets-oncogene transcription factor, highly correlates with malignant phenotype of malignant melanoma through up-regulation of the membrane-type-1 matrix metalloproteinase gene.
Matrix metalloproteinase (MMP) is closely involved in the degradation of extracellular matrix and confers invasive and metastatic potential to malignant tumors. MMP-2 is a type-IV collagenase secreted as a proenzyme that is activated on the surface of the tumor cell by membrane-type 1-MMP (MT1-MMP). MT1-MMP plays a critical role during tumor progression and metastasis. We investigated the expre...
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ژورنال
عنوان ژورنال: Journal of Cancer
سال: 2018
ISSN: 1837-9664
DOI: 10.7150/jca.25082